—
—
In Stock
Melanotan 1, also known as Afamelanotide, is a synthetic analog of the naturally occurring peptide hormone alpha-melanocyte-stimulating hormone (α-MSH). It was originally developed to promote skin tanning without exposure to harmful UV rays. Key Facts - Chemical Name: Afamelanotide - Molecular Formula: C78H111N21O19 - CAS Number: 75921-69-6 - Type: Synthetic peptide; melanocortin receptor agonist How It Works Melanotan 1 binds primarily to melanocortin 1 receptors (MC1R) on melanocytes (pigment-producing cells in the skin), stimulating the production of melanin—the pigment responsible for skin color. This leads to a gradual darkening of the skin, offering a protective effect against UV damage. Uses and Benefits - 🌞 Sunless Tanning: Stimulates natural tanning, reducing the need for UV exposure. - 🛡️ Photoprotection: Used to reduce UV-induced skin damage in people with photosensitive conditions. - 🧬 FDA-Approved for EPP: Marketed under the brand name Scenesse, it is approved for erythropoietic protoporphyria (EPP)—a rare genetic disorder causing painful sensitivity to sunlight. Administration - Typically delivered via a subcutaneous implant (especially in clinical settings). - Effects build up gradually and can last several weeks to months, depending on dosage and skin type. Side Effects While generally well-tolerated, potential side effects may include: - Nausea - Flushing - Headaches - Injection site reactions - Darkening of moles or freckles Melanotan 1 vs. Melanotan 2 Feature Melanotan 1 Melanotan 2 Receptor Selectivity Highly selective for MC1R Binds MC1R and others (e.g., MC4R) Tanning Effect Gradual, more natural-looking Stronger, faster tanning Side Effects Fewer side effects More side effects (e.g., libido changes) Medical Use FDA-approved (Scenesse) Not approved for human use
